“白鼻子”病貉血液常规生化指标的测定分析

摘要

为了分析貉“白鼻子”病的发病原因,对该病患貉与健康貉各9只的20项血液常规生化指标进行了测定,并用Mann-whinney法进行了组间差异性检验.与正常貉相比:病貉门冬氨酸氨基转移酶(p=0.024)、谷氨酰转移酶(p=0.036)、总胆红素(p=0.019)水平升高,白蛋白(p=0.040)及白球比(p=0.031)下降,这些生化指标的异常提示病貉肝脏的蛋白合成代谢功能下降,胆红素代谢异常,肝脏受到了损失；病貉肌酐(p=0.041)水平的降低,α-羟丁酸脱氢酶(p=0.017)水平的升高,可能与“白鼻子”病貉患有贫血有关；病貉肌酸激酶(p=0.019)水平的升高可能与病貉患有的肌肉萎缩有关.%An experiment was conducted to detect the blood routine biochemical parameters for nine raccoon dogs with White Nose Disease (WND) and nine healthy raccoon dogs in order to find out the pathogenesis of WND. The data were analyzed by the method of Mann-Whitney test. Compared with the healthy raccoon dogs, the AST, GGT, and TBIL levels of the raccoon dogs with WND increased, while ALB and TP levels declined. There were significant differences in those indexes between the raccoon dogs with WND and the healthy ones (p<0.05). The abnormality of biochemical parameters indicated that the liver of the raccoon dog with WND was impaired. The CREA level of the raccoon dogs with WND declined and α-HBDH level rose, which may relate to their anemia. An increase in CK level may relate to the muscular atrophy.