目的:从药物经济学角度,对中晚期乳腺癌化疗中两种止吐方案进行分析评价.方法:对100例所用化疗方案剂量以及辅助用药完全相同的中晚期乳腺癌患者,按昂丹司琼+地塞米松、格拉司琼+地塞米松两种止吐方案分成两组,运用药物经济学成本-效果分析法进行评价.结果:2种方案止吐的有效率及不良反应率比较均无统计学差异(P＞0.05);两种方案的C/E分别为8.03和5.36,(P＜0.01).结论:两种方案中,格拉司琼+地塞米松治疗方案的效果较好.%Objective: To explore the effects of different antiemetic project in breast cancer chemotherapy from pharmacoeconomics. Methods: Total of 100 cases of chemotherapy breast cancer patients were randomly divided into two groups. They were treated with ondansetron + dexamcthasone ( DXM ), ganisctron + DXM respectively. The schemes were evaluated with pharrcoeconomic cost - effectiveness analysis. Results: The difference of effective rates between the two groups was not significant. The cost - effectiveness ratios were 8.03 and 5.36 ,there was significant difference in the two groups. Conclusion: The granisetron + DXM regimen is the most effective and inexpensive for the antienetic treatment of breast cancer.
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