三维适形放疗联合微波热疗治疗颈部淋巴结转移癌的疗效观察

摘要

Objective:To observe the efficacy to malignant tumors migrated to neck lymph - nodes treated by three dimensional conformal radiotherapy combined with microwave hyperthermia. Methods: Fifty - five patients diagnosed as nasopharyngeal carcinoma, lung cancer, larynx carcinoma, oesophagus carcinoma which have migrating to neck lymph - node were divided to three dimensional conformal radiotherapy combined with microwave hyperthermia ( R +H ) group and three dimensional conformal radiotherapy( R ) group. Radiotherapy DT were 60 - 70Gy, six times a week, microwave hyperthermia were used three times a week. All patients were followed - up for 2 months and observed the efficacy. Results: After treatment,in the R + H group,the total subsudised rate of neck lymph - nodes was 76.7％( 23/30 ), whereas in R group, the total subsudised rate of neck lymph - nodes was 35.0％ ( 7/25 )( P ＜ 0.05 ). After follow - up for 3 months,in R + H group, the total subsudised rate of neck lymph - nodes was 83.3％(25/30),whereas in R group,the total subsudised rate of neck lymph -nodes was 60.0％( 15/25 )( P ＜ 0.05 ).There were no obvious side - effcets. Conclusion: Three dimensional conformal radiotherapy combined microwave hyperthermia has better efficacy than radiotherapy alone to neck lymph -nodes which malignant tumors migrated.%目的:观察三维适形放疗配合微波热疗对颈部淋巴结转移性癌的治疗效果.方法:对55例来源于鼻咽癌、喉癌、食管癌及肺癌的颈部淋巴结转移性癌,分为微波热疗+三维适形放疗组30例及单纯三维适形放疗组25例,放疗总量60-70Gy/30-35次;6次/周;微波热疗3次/周,随访3个月,观察疗效.结果:两组患者全部完成治疗计划.微波热疗+三维适形放疗组患者在治疗结束时颈部肿块完全消退23例(76.7%),单纯三维适形放疗组患者为7例(35.0%),两组比较差异有统计学意义(P＜0.05).随访结束时微波热疗+三维适形放疗组患者颈部肿块完全消退25例(83.3%),单纯三维适形放疗组为15例(60.0%),两组比较差异有统计学意义 (P＜0.05).无明显不良反应.结论:三维适形放疗联合微波热疗对治疗颈部淋巴结转移性癌疗效良好.