超声引导下经皮盐酸局部注射治疗原发性肝癌的临床研究

摘要

目的:观察 超声引导下经皮盐酸局部注射治疗肝癌的临床疗效及安全性.方法:20例原发性肝癌患者采用B超引导下局部注射6mmol/L稀盐酸,观察病灶原位灭活率、影像学、组织学改变、不良反应及生存率.结果:直径＜3cm、3cm-5cm,>5cm 肿瘤的治疗有效率分别为100%、88.9%、50%;半年生存率100%,1年生存率80%.主要副作用为局部疼痛、发热,无严重不良反应发生.结论:超声引导下经皮盐酸局部注射治疗原发性肝癌是一种安全、有效的治疗手段.%Objective: To evaluate the effects and safety of ultrasonography mediated percutaneous hydrochioric acid injection threapy for primary hepatocellular carcinoma. Methods:Twenty patients of primary hepatocellular carcinoma were treated intratumor or injection of 6 mmol/L hydrochloric acid. The in situ destructive rate, imaging and histopathology evaluation, side effects and survival rate were observed. Results :The efficiency rates of tumor diameter ≤3cm,3cm-5cm, ＞5cm were 100％ , 88.9％ , 50％ , respectively. The overall survival rates at 6 mouths,1 year were 100％ , 80％ , respectively. Complications included pain and fever, and no severe complication was found.Conclusion:The ultrasonography mediated percutaneous hydrochioric acid injection threapy is a effective and safe method for treatment of primary hepatocellular carcinoma.