经单鼻孔蝶窦入路显微手术切除垂体腺瘤126例分析

摘要

Objective: To review the experience of transsphenoidal approach for removal of pituitary adenoma.Methods :Total of 126 patients with pituitary adenoma were treated with transsphenoidal surgery. Results:Total removal was achieved in 89 cases, subtotal in 31 cases. All patients revealed improvement visual acuity and pituitary function. After the operations, 18 patients develope diabetes insipidus, CSF leakage in 13 cases, 3 cases with hemorrhage , all were cured. Conclusion: Transsphenoidal approach is a safe, convenient and minimal -invasive approach in the treatment of pituitary adenomas. This approach is the first choice in most cases with pituitary adenoma.%目的:探讨经单鼻孔-蝶窦入路显微手术切除垂体腺瘤的临床意义.方法:对126例垂体腺瘤病人采用经单鼻孔-蝶窦入路显微手术切除.结果:全切除89例,次全切31例,部分切除6例,病人视力症状及内分泌功能术后均有改善.术后尿崩症18例、脑脊液漏13例、术腔血肿3例,经再次手术治疗均治愈.结论:经单鼻孔-蝶窦入路切除垂体腺瘤具有微创、安全、简便等优点,是大部分垂体腺瘤的首选手术方式.