丹参酮IIA防治老年放射性脑损伤临床观察

摘要

Objective:To observation the protective effect of Tanshinone ⅡA in radiation - induced senile brain injury. Methods: To compare 108 patients treated by Tanshinone IIA combined radiotherapy for brain metastases to 104 patients treated by radiotherapy alone. Results: The patients treated by Tanshinone ⅡA combined radiotherapy had significantly benefit in radiation brain injury with the patients treated by radiotherapy alone respectively ( P ＜0.05 ). Conclusion: Tanshinone ⅡA can inhibit radiation -induced brain injary.%目的:观察丹参酮IIA防治老年放射性脑损伤临床疗效.方法:回顾性分析108例脑转移瘤丹参酮IIA联合放疗和104例脑转移瘤单纯放疗的老年脑转移患者的放射性脑损伤发生情况.结果:丹参酮IIA联合放疗组与单放疗组在防治放射性脑损伤方面差异有统计学意义(P<0.05).结论:丹参酮IIA对老年脑转移瘤的放射治疗具有一定的辐射防护作用.