肺乳头状腺瘤临床病理观察

摘要

Objective : To investigate the clinicopathology features of papillary adenoma of the lung.Method : Morpholoical obaervation and immunohistochemistry was applied for one case of papillary adenoma of the lung, and the literatures were also reviewed.Results : The malignant cells were arranged in papillary and adenoma with the well differentiated pulmonary alveolus epithelium,cells grew with a line, the surface cells were cubic, nucles were normally atained and caryokinesis were invisible.Immunohistochemically, the tumor cells were positive for CK and ITF - 1,storomal were posinve for Vimennn and Actin.Conclusions: PapiUary adenoma of the lung is a rare tumor, which is easy to be confused with sclerosing and alveolar adenoma and papillary carcinoma.%目的:探讨肺乳头状腺瘤的临床病理特点.方法:应用光镜、免疫组化染色等方法对我院一例肺乳头状腺瘤进行分析,并复习文献.结果:肿瘤为分化成熟的肺泡上皮细胞构成腺管,由乳头状、团块状结构及纤维间质构成.腺管和乳头上皮多为单层排列,细胞呈立方状,核淡染,无核分裂.免疫组化示瘤细胞CK(++), TTF-1(++), 间质Vimentin(++), Actin(+).结论:肺乳头状腺瘤是一种罕见的良性肿瘤,易与硬化性血管瘤、肺泡性腺瘤、乳头状腺癌混淆.