目的:回顾性分析本院352例子宫内膜癌患者的临床资料,总结近年来我院子宫内膜癌患者的临床特点.方法:将本院2003年6月至2010年9月确诊子宫内膜癌患者352例临床病理资料分为两个年龄组:即年轻妇女组(≤40岁)及中老年妇女组(＞40岁).年轻妇女组46例,中老年妇女组306例,比较年轻妇女与老年妇女子宫内膜癌的临床特点、临床病理类型以及对术前术后诊断的差异性.结果:352例子宫内膜癌患者中老年妇女患病率显著高于年轻组占86.9％ (306/352),两组患者在民族、居住地区及合并肥胖、糖尿病史方面差异无统计学意义(P＜0.05)；在文化程度、不孕史、服用激素史、合并高血压病方面差异有统计学意义(P＜0.05),但是文化程度在中老年妇女组内部差异有统计学意义(P＜0.05).在每组内部城市和农村患病率有统计学意义(P＜0.05).两组病理类型均以子宫内膜样腺癌Ⅰ期,G1,浅肌层浸润为主.结论:老年子宫内膜癌患者的临床病理类型及肌层浸润深度与年轻患者相似.年轻组病理组织学分级中高分化所占比率高于年老组,中分化-低分化子宫内膜癌所占比率低于老年组,具有统计学意义.文化程度、不孕史、服用激素史,实际上均与这两个年龄阶段的社会人文环境有关,可能与子宫内膜癌疾病本身关系不大.对于早期、高分化的年轻(≤40岁)子宫内膜癌患者可考虑保留生育功能的治疗.%Objective:Analyzed retrospectively data of 352 cases of endometrial cancer. Methods: All 352 patients diagnosed with endometrial cancer were divided into two age groups: Young women's group ( ≤40 years) and elderly womens group ( >40 years) , 46 cases of young women 306 patients were in middle - aged women's group. Results: Of 352 cases of endometrial cancer older women were significantly higher than the younger group ( ≤40 years) accounted for 86.9% (306/352), two groups of patients in the nation, residential areas and combined with obesity, diabetes mellitus was no statistical different significance ( P > 0.05); in education, infertility history, history of taking hormones, patients with hypertension was significantly different (P<0.05). Conclusion: Elderly patients with endometrial cancer of clinical pathology and depth of myometrial invasion similar to younger patients. In younger group histological grade was higher than the old well - differentiated group.
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