目的:探讨纵隔异位胰腺的临床病理特点.方法:对我院收治的1例发生于纵隔的异位胰腺的临床表现、组织形态学及免疫组化进行分析,并复习相关文献.结果:患者,男,27岁,一般情况良好,无发热、胸痛、咳嗽和呼吸困难.光镜下可见胰腺导管及腺泡为病变的单一组成成分,细胞分化良好,没有异型性.免疫组织化学染色显示肿瘤细胞CK(AE1/AE3)和AACT阳性；CgA、Syn、Calretinin、TTF-1和CEA阴性.结论:纵隔异位胰腺十分罕见,需充分取材并排除畸胎瘤的可能,方可诊断.当年轻患者在纵膈发现巨大囊肿,又无明显症状,应该考虑异位胰腺.%Objective: To research the clinical pathological features of ectopic pancreas in the mediastinum. Methods; The clinical manifestations, histopathological features and immunohistochemical results were analyzed in one case of ectopic pancreas in the mediastinum, with review of the related literatures. Results: The patient was a 27 years -old man without fever, chest pain, cough and dyspnea. Microscopically, the lesion was consisted of pancreatic acinary and ductal structures, with epithelial cells having no atypia. Immunohistochemieally, these cells were positive for CK( AE1/AE3) and AACT; negative for CgA, Syn, Calretinin, TTF - 1 and CEA. Conclusion; Ectopic mediastinal pancreas is rare. We can diagnose ectopic pancreas when teratoma is excluded in the completely processed material. If a young man has a large cystic lesion in the mediastinum, having no specific symptoms, ectopic pancreas should be considered.
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