25例多原发癌临床分析

摘要

目的:探讨多原发癌的临床特点、间隔时间、治疗方法及预后.方法:对北京市中关村医院肿瘤科2006年1月-2010年12月收治的多原发癌进行回顾性分析.结果:本组25例病例占同期收治病例数的2.6％,其中男性10例,女性15例,男女比例2∶3.首发癌和重复癌的间隔时间为2月-45年.首次发病年龄、性别、治疗方法与发病间隔时间比较,其中首次发病的年龄与发病间隔时间有显著相关性(P ＜0.001).发病间期是影响预后的主要因素,发病间期越短,预后越差(P＜0.01).手术治疗后生存期较长,但无统计学意义.结论:及时发现多原发癌,以便及时治疗,延长生存期.%Objective:To elucidate the clinical features,the interval between the two cancers,treatment and prognosis of the multiple primary cancers (MPC).Methods:All 25 cases of the multiple primary cancers were analysed retrospectively in Zhongguancun Hospital from 2006 to 2010.Results:These cases accounted for 2.6％ of all the hospitalized patients in the same period among which 10 were males and 15 were female with sex ratio of male and female 2∶ 3.The interval between the two cancers was 2 months to 45 years.The age of first cancer and the interval of the two cancers was significantly correlated(P ＜0.001) with the prognosis.The interval between the 2 cancer played crucial part affecting the prognosis(P ＜ 0.01).The survival time was longer in the patients of the surgery treatment,but without significance.Conclusion:The multiple primary cancers (MPC) found in early stage and actived treatment measures in time,can prolong the patients' survival time.