CTOP方案治疗恶性淋巴瘤疗效观察

摘要

目的:观察CTOP方案治疗恶性淋巴瘤的疗效.方法:应用CTOP方案治疗我院收治的32例恶性淋巴瘤患者,2个疗程后评价疗效.结果:32例恶性淋巴瘤患者,其中弥漫大B细胞淋巴瘤20例,套细胞淋巴瘤6例,T细胞性淋巴瘤4例,伯基特淋巴瘤2例,均为初治病人.予CTOP方案治疗2疗程,结果CR 50％(16例),PR 25％(8例),总有效率为75％(24例).毒副反应中骨髓抑制为中度,胃肠道反应轻微.心脏毒性表现为心律失常、ST-T改变等,停药后均可恢复.肝肾毒性轻微.结论:CTOP方案是治疗恶性淋巴瘤的有效方案,可作为一线方案在临床应用.%Objective:To observe the effect of CTOP scheme for malignant lymphoma.Methods:To treat 32 cases of malignant lymphoma patients by CTOP regimen.Results:Of 32 cases of malignant lymphoma there were diffuse large B cell lymphoma 20 cases,6 cases of lymphoma cells,T cell sex lymphoma 4 cases,burkitt lymphoma in 2 cases.CR was 50％ (16 cases),PR 25％ (8 cases),with the total effective rate 75％ (24 cases).Adverse reaction were bone marrow suppression,gastrointestinal reaction,cardiac toxicity.Conclusion:CTOP scheme is effective for malignant lymphoma.