子宫颈CIN病变切缘阳性的临床病理因素分析

摘要

Objective:to study the cervical CIN lesions related factors of the cone cutting after cutting edge posi-tive.Methods:A retrospective analysis was performed for vaginal mirror cervical biopsy diagnosis of cervical intraepi-thelial neoplasia(CIN)and accept the cervical cone cut method.All 4527 cases of patients,the patients'age,degree of pathological changes,lesions scope,operation method and whether menopause and the cervical cone cutting and cut-ting edge positive rate for single factor and multiple factors analysis.Results:Multiariable logistic regression analysis found that the operation method is the scope,degree of disease,menopausal status,pathological changes and the cut edge positive highly relevant factors,the relative risk of 7.8735,5.0352,4.1055,4.5571,respectively.Conclusion:Cervical lesion degree of serious,large range of lesions,postmenopausal is cervical LEEP cone cutting operation cut-ting edge positive risk factors ,in the cervical cone cutting operation method choice should attach importance to it.%目的：探讨子宫颈CIN病变锥切术后切缘阳性的相关因素。方法：回顾性分析经阴道镜子宫颈活检诊断为宫颈上皮内瘤变（cervical intraepithelial neoplasia，CIN）并接受宫颈锥切术的患者4527例，对患者年龄、病变程度、病变范围、手术方式及是否绝经与子宫颈锥切术切缘阳性率作单因素和多因素分析。结果：多因素logistic回归分析发现，手术方式、病变程度、是否绝经、病变范围是与切缘阳性高度相关的因素，相对危险度分别为7．8735、5．0352、4．1055、4．5571。结论：宫颈病变程度严重、病变范围大、LEEP、绝经后是宫颈锥切术切缘阳性的高危因素，在宫颈锥切手术方式选择时应予以重视。