结直肠癌术后脂肪液化感染的脓液培养及感染源分析

摘要

目的：探讨结直肠癌术后脂肪液化感染的脓液的致病细菌及感染源，为防治术后感染提供参考，以降低结直肠癌患者术后感染率。方法：回顾分析2013年1月至2014年1月274例结直肠癌患者的临床资料，对术后脂肪液化感染的脓液做细菌培养，鉴定病原菌并就手术患者的年龄、性别、体质量指数、手术方式、手术时间、DuKes分期及是否使用抗菌药物等与术后脂肪液化感染的关系进行分析研究。结果：77例患者发生术后脂肪液化感染，感染率为28.1%。77例感染患者共分离出84株病原菌，以大肠埃希菌（33.33%）、金葡菌（16.67%）、铜绿假单胞菌（17.86%）为主。感染患者的BMI指数、手术时间、是否应用抗菌药物、DuKes分期存在统计学差异（ P﹤0.05）。结论：结直肠癌患者发生术后感染与体质量指数、手术时间、是否使用抗菌药物、DuKes分期有较为密切的关系。%Objective:To investigate the liquefied fat after colorectal cancer surgery infection-causing bacteria and infectious pus,and provide reference for prevention of postoperative infection,to reduce postoperative infection rates of colorectal cancer patients. Methods:Retrospectively analyze the clinical data of 274 cases of colorectal cancer patients by postoperative infections fat liquefaction of pus bacterial culture,identification of pathogens and the surgery the patientˊs age,gender,body mass index,surgical approach,operative time,DuKes stage and whether the relationship between the use of antimicrobial drugs,and postoperative infections fat liquefaction. Results:77 patients with postop-erative fat liquefaction postoperative infection,the infection rate was 28. 1%,77 cases of infection were isolated 84 pathogens,Escherichia coli(33. 33%),Staphylococcus aureus(16. 67%),Pseudomonas Pseudomonas(17. 86%) dominated. Infected patients BMI index,operative time,whether the use of antimicrobial drugs,DuKes stage had statis-tically significant differences(P﹤0. 05). Conclusion:In patients with colorectal cancer incidence of postoperative infection was related with body mass index,operative time,use of antimicrobial drugs,DuKes staging.