纳米碳示踪剂在30例甲状腺癌手术中的应用

摘要

Objective:To discuss the clinical effect of the nano -carbon tracer applied in 30 cases thyroid gland carcinoma operations.Methods:The 60 cases thyroid gland carcinoma patients were divided into nano -carbon group and control group.All the patients underwent the thyroid gland total resection and Ⅵ region lymph nodes dissection operations.The nano -carbon group applied the nano -carbon tracer during the neck dissectioin operation and without the application in control group.The lymph nodes dissection numbers,postoperative serum blood calcium levels,serum parathyroid hormone levels in 2 groups were compared.Results:The average number of lymph nodes in nano -carbon group was 6.5 and 3.2 in control group(P <0.05).There was 1 transient hypocalcemia in patients in nano -carbon group after the operation and 12 transient hypocalcemia in patients in control group(P <0.05).There were 2 cases temporary decline in patients with parathyroid hormone and 9 cases in control group(P <0.05).Conclusion:The ap-plication of the nano -carbon tracer improved the thyroid gland carcinoma patients Ⅵ lymph nodes dissection number obviously,the nano -carbon tracer application during the operation contribute to the identification and protection para-thyroid gland function.%目的：探讨纳米碳示踪剂在30例甲状腺癌手术中的应用效果。方法：将60例甲状腺癌患者随机均分为纳米炭组和对照组，行甲状腺全切及患侧Ⅵ区颈部淋巴结廓清术，纳米炭组在行淋巴结廓清术前应用纳米炭示踪剂，对照组不使用，比较2组患者的淋巴结清扫数目、术后血钙水平及甲状旁腺素（PTH）水平。结果：纳米炭组每例患者平均清扫淋巴结6．5枚，对照组3．2枚（P ＜0．05）；纳米炭组术后发生一过性低钙血症患者1例，对照组12例（P ＜0．05）；纳米炭组术后发生 PTH 暂时下降的患者2例，对照组9例（P ＜0．05）。结论：纳米炭淋巴示踪剂的应用可明显提高甲状腺癌患者Ⅵ区淋巴结的清扫数目，术中有助于甲状旁腺的识别并保护甲状旁腺的功能。