胸部肿瘤调强放疗后动态心电图异常的临床分析

摘要

Objective:To analyze breast cancer IMRT dynamic ECG abnormalities in patients with IMRT effect on the heart. Methods:Total of 109 cases as observation group,110 cases of breast cancer using conventional radiothera-py patients as a control group. Contrast were observed after radiotherapy for the patient ECG abnormalities. Results:Incidence of emergence increased, and the control group was significantly higher than that observed patients. After treatment,patients with abnormal ECG dynamic contrast was increased significantly. Arrhythmias contrast,at the end of treatment,the incidence was significantly higher than before treatment. Conclusion:IMRT for breast cancer patients in the early cardiotoxicity focused radiotherapy,cardiac toxicity after radiotherapy will be reduced. Comparing conven-tional radiotherapy,intensity-modulated radiotherapy for patients with cardiac toxicity is small.%目的：：分析胸部肿瘤调强放疗后动态心电图异常，观察调强放疗对患者心脏的影响。方法：选取从2012年3月到2013年3月收治的需要接受调强放疗的胸部肿瘤患者共109例为观察组，同时选择110例采用常规放疗的胸部肿瘤患者作为对照组。对比观察两组患者接受放疗后，患者心电图的异常情况。同时观察调强放疗患者动态心电图治疗前、治疗后以及治疗半年后的异常情况。结果：对比观察组和对照组在治疗前、治疗后以及治疗半年后出现异常心电图的发生率。两组患者在治疗结束后其异常动态心电图发生率均出现明显升高，并且对照组明显要高于观察组患者。患者在治疗后出现动态心电图异常对比治疗前有显著增加，治疗前和治疗结束两组数据对比有统计学差异。治疗前和治疗结束半年后患者出现窦性心律失常、偶发房室性心律失常以及频发房室性心律失常的发生率对比，治疗结束后的发生率明显要高于治疗前。不同治疗方案对比异常心电图各项指标没有统计学差异。结论：调强放疗对胸部肿瘤患者的心脏毒性主要集中在放疗的早期，在放疗结束后心脏毒性会相对减少。对比常规放疗方法，调强放疗对于患者心脏毒性要相对较少。