妊娠合并卵巢肿瘤的临床诊断和妊娠结局分析

摘要

Objective:To investigate the clinical Pregnancy diagnosis of ovarian cancer and Pregnancy outcomes, infection Prevention measures. Methods:Randomly selected 75 Pregnant women with ovarian cancer as the observation grouP,75 cases with tumor-like lesions with Pregnancy in the same Period as the control grouP. Clinical manifesta-tions,laboratory exam were observed and to analyze the outcome of Pregnancy. Results:Pregnancy ovarian tumors usu-ally had no obvious clinical symPtoms. In observation grouP 46 cases CA125 increased,with an average of(31. 53 ± 14. 73)U/ml,in the control grouP CA125 increased in 41 cases with an average of(29. 27 ± 12. 23)U/ml(P>0. 05). There were no differences in CA199,CEA,AFP. Ovarian tumors in Pregnancy to full-term Pregnancy out-come,accounting for 74. 67% of all rather Premature birth and miscarriage of 25. 33% of the total. And in different time Periods with different Pregnancy outcomes,<12 weeks to abortion based,and 12-28 weeks Premature birth and abortion was more. >28 weeks-term Places full-term oriented. Conclusion:Pregnancy ovarian tumors are usually no clinical symPtoms,ultrasound and laboratory tests can helP the differential diagnosis,and early intervention is cru-cial to Pregnancy outcome.%目的：探讨妊娠合并卵巢肿瘤的临床诊断和妊娠结局，总结预防感染措施。方法：随机选取2011年2月-2013年4月75例妊娠合并卵巢肿瘤患者为研究对象，作为观察组，同时期的75例妊娠合并瘤样病变患者为对照组。从临床表现、辅助检查上比较妊娠合并卵巢肿瘤患者临床特征，并分析其妊娠结局，观察采取预防感染措施后感染发生情况。结果：妊娠合并卵巢肿瘤通常无明显的临床症状，有症状则以恶心呕吐、腹痛等为主。和瘤样病变比较，其肿瘤直径增大明显，肿瘤血流阻力指数下降，孕期肿块均较瘤样病变明显。观察组CA125增高46例，平均值为（31.53±14.73）U/ml，对照组 CA125增高41例，平均值为（29.27±12.23）U/ml，两组比较无明显差异性（ P＞0.05）。两组患者CA199、CEA、AFP检测结果比较差异无统计学意义，均在正常范围内。妊娠合并卵巢肿瘤的妊娠结局以足月产为主，占全部的74.67%，早产和流产占全部的25.33%。在不同时间段有不同的妊娠结局，＜12周以流产为主，12-28周以早产和流产较多，＞28周-足月则以足月产为主。感染发生率为4%。结论：妊娠合并卵巢肿瘤通常无临床症状，超声和实验室检查有助于鉴别诊断，早期干预对妊娠结局至关重要。