甲状腺髓样癌的超声特征及病理学分析

摘要

目的:分析甲状腺髓样癌(medullary thyroid carcinoma,MTC)的超声特征与病理的相关性.方法:选取2014年10月至2017年1月在我院病理确诊的16例MTC(20个病灶)患者的超声资料,同时收集甲状腺乳头状癌(PTC)23个结节的超声资料作为对照,分析两组结节的声像图特征.结果:本研究中10例MTC患者单发,11例MTC位于中上极,15例MTC边界清晰,大多呈椭圆形,内部可见钙化者14例(其中粗大钙化12例),伴有淋巴结转移者12例,大多无包膜或包膜不完整.结论:MTC与PTC结节在位置、边界、边缘、形态、A/T及钙化之间的差异有统计学意义(P＜0.05),但就MTC其自身的声学特征而言与良性甲状腺结节有许多类似之处,单独超声诊断具有一定难度,更需要结合临床及相关的实验诊断结果,才能进一步提高MTC的诊断水平.%Objective:To analyze the sonographic features and pathologic correlation of medullary thyroid carcinoma.Methods:Selecte 16 cases of MTC patients from October 2014 to January 2017 in our hospital.At the same time,in order to analyze two kinds of nodule of the features of isofocies map,we collected 23 cases of PTC to compared with it.Results:In this study, 10 patients were single, 11 patients located in the upper pole.15 patients of boundary were clear,most of them were oval.There were 14 patients who were calcified.12 cases that were related with lymphatic metastasis, mostly had no capsule or incomplete capsule.Conclusion:The differences between MTC and PTC in location, border, edge, shape, A/T and calcification had the meaning of statistics.However, there are many similarities between MTC itself and benign thyroid nodules, there are some difficulties in signgle ultrasound diagnosis.So we need the result of clinic and experimental diagnosis.They can help improve the diagnosis level of MTC.