Objective:To understand the incidence and mortality of breast cancer in Chongqing.Methods:Breast cancer cases(ICD-10:C50) were collected from 11 cancer registration sites in Chongqing in 2015.Incidence,mortality,age-standardized incidence rate by Chinese standard population,age-standardized mortality rate by Chinese standard population,proportion and sequence were analyzed by SРSS 19.0.The difference of incidence and mortality between urban and rural area was compared by Chi-square test.The trend change of age specific incidence and mortality was tested by trend chi-square test.Results:The crude incidence of breast cancer among women was 31.48/105 in 11 cancer registration sites,Chongqing in 2015.The crude incidence among urban women(42.07/105) was higher than it among rural women(26.32/105)(P=0.002).The age-standardized incidence rate by Chinese standard population was 24.20/105.The incidence of breast cancer was the second in all cancers among women in 2015,which accounted for 6.00%.The mortality of breast cancer was 7.33/105.The mortality of breast cancer among urban women(8.77/105) was not different compared to it among rural women significantly(6.62/105)(P=0.099).The age-standardized mortality rate by Chinese standard population was 4.96/105.The mortality of breast cancer listed the sixth in all cancers among women,which accounted for 2.10%.The incidence of female breast cancer was below 5/105 before 25 years old.It increased rapidly after 25 years old and reached the peak in 50 age group,then decreased with the age.The mortality of female breast cancer was below 5/105 before 40 years old.It increased rapidly after 40 years old and reached the peak in 80 age group.The truncated incidence of breast cancer was 56.01/105.The truncated incidence of breast cancer among urban women(67.91/105) was higher than it among rural women(50.55/105)(P=0.001).The truncated mortality of breast cancer was 10.75/105.The truncated mortality of breast cancer among urban women(11.96/105) was similar to it among rural women(10.42/105)(P=0.136).The cumulative risk of breast cancer was 2.27%.The cumulative risk of breast cancer incidence among urban women(3.07%) was higher than it among rural women(1.93%)(P=0.039).The cumulative risk of breast cancer mortality was 0.51%.Conclusion:The incidence and mortality of female breast cancer was higher in Chongqing.The tertiary prevention measure should be implemented according to the different characteristic of female breast cancer between urban and rural women.%目的:了解重庆市女性乳腺癌发病与死亡现状,为开展乳腺癌防治提供建议.方法:收集整理2015年重庆市11个肿瘤登记点报告的乳腺癌(ICD-10编码为C50).采用SPSS 19.0统计分析发病率、死亡率、标化发病率、标化死亡率、构成比、顺位.不同地区间乳腺癌发病率与死亡率的比较采用χ2检验,年龄别发病率与死亡率趋势分析采用趋势χ2检验.结果:2015年11个肿瘤登记点女性乳腺癌粗发病率为31.48/10万,城市发病率(42.07/10万)高于农村(26.32/10万),差异有统计学意义(P=0.002),乳腺癌标化发病率为24.20/10万,在女性恶性肿瘤中顺位居第2位,占6.00%.女性乳腺癌粗死亡率为7.33/10万,城市(8.77/10万)与农村乳腺癌死亡率(6.62/10万)差异无统计学意义(P=0.099),乳腺癌标化死亡率为4.96/10万,在恶性肿瘤死亡顺位中居第6位,占2.10%.女性乳腺癌发病率25岁前低于5/10万,25岁后快速上升,50岁~年龄组达到高峰,随后下降.女性乳腺癌死亡率在40岁前低于5/10万,40岁后呈上升趋势,80岁~年龄组达到高峰.女性乳腺癌截缩发病率为56.01/10万,城市(67.91/10万)高于农村(50.55/10万),差异有统计学意义(P=0.001).截缩死亡率为10.75/10万,乳腺癌截缩死亡率城市(11.96/10万)与农村(10.42/10万)比较差异无统计学意义(P=0.136).发病累积危险度为2.27%,城市(3.07%)高于农村(1.93%),差异有统计学意义(P=0.039).死亡累积危险度为0.51%.结论:重庆市女性乳腺癌发病率与死亡率较高,应针对城乡女性乳腺癌发病死亡特点开展三级预防.
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