绝经前子宫内膜癌临床特征及诊断

摘要

Objective:To analyze the clinical characteristics and diagnosis of pre -menopausal endometrial car-cionma.Methods:Data of 208 cases of premenopausal endometrial cancer (EC)was retrospectively analyzed.Re-sults:Premenopausal cases accounted for 28.97% of the total EC patients during the same period (208 of 718)."Abnormal vaginal bleeding"was the most common complaint (5 1 .4%)and patients were mostly at stage Ⅰ.While patients with the complaint of"abdominal mass"were mostly at stage Ⅲ-Ⅳ.Patients under 45 years old with diag-nosis coincidence of 58.8%were characterized with shorter confirmed diagnosis time and higher B-ultrasound detec-tion rate than the others(72.5% vs 58.19%).The diagnosis accordance rate of patients of stage Ⅰwas higher than those of stage Ⅱ-Ⅳ.Conclusion:Pre -menopausal EC usually occurs in perimenopausal period and the clinical symptoms are not typical.The low diagnostic accordance rate and the confirmed diagnosis time increased with the age.%目的：分析绝经前子宫内膜癌的临床特征及其诊断。方法：回顾性分析2005年5月－2015年5月间208例绝经前子宫内膜癌（EC）病例，以提高EC的临床诊断水平。结果：绝经前EC患者共208例，占同期EC的28．97％（208／718）。以45岁为界，分A、B两组，A组为38．46％（80／208）；B组为61．54％（128／208）。以“阴道异常出血”主诉最多（51．4％），且多为Ⅰ期，而以“腹部包块”为主诉多为Ⅲ－Ⅳ期；诊断符合率为58．8％，其中，A组患者较B组患者确诊时间短，B超检出率高（72．5％ vs 58．19％），Ⅰ期患者诊断符合率明显高于Ⅱ－Ⅳ期患者。结论：绝经前EC大多于围绝经期发病，临床症状不典型，诊断符合率较低，确诊时间随年龄增加而延长。