首页> 中文期刊> 《现代肿瘤医学》 >18 F-FDG符合线路显像在直肠癌术后局部复发中的诊断价值

18 F-FDG符合线路显像在直肠癌术后局部复发中的诊断价值

         

摘要

目的:评价18 F-FDG符合线路显像诊断直肠癌术后复发的价值,并与CT结果比较。方法:27例直肠癌术后患者,经病理活检或临床随访证实为术后复发者15例,无复发者12例。所有患者行18 F-FDG符合线路显像及CT平扫或增强,分析两种方法的诊断效能。结果:本研究中18 F-FDG符合线路显像诊断直肠癌术后复发的阳性预测值及准确性(93.3%、92.6%)均高于CT(86.7%、88.9%),但两者诊断的阴性预测值无明显差异(91.7%、91.7%)。27例患者均行CEA测定,15例CEA阳性患者中9例术区病变有FDG代谢,病理或随访证实该9例患者均为复发。12例CEA阴性患者中有3例患者术后局部有软组织密度影且FDG代谢明显增高。结论:18 F-FDG符合线路显像是诊断直肠癌术后局部复发敏感而有效的方法,值得临床推广应用。%Objective:To evaluate the diagnostic value of 18 F - FDG dual head gamma - camera coincidence ( DHC)imaging in the local recurrence of postoperative rectal cancer. Methods:DHC was studied between November 2013 and April 2015 on 27 patients(9 women,18 men,mean age:55. 6 years old)highly suspected recurrence. DHC imaging and contrast-enhanced computed tomography( CT)findings were compared with histopathological findings and/or clinical follow-up data as the"gold standard". Results:The positive predictive value and accuracy of DHC imaging(93. 3%,92. 6%)was higher than CT(86. 7%,88. 9%). While the negative predictive value between the two imaging had no significant difference. All of the 27 cases were performed CEA measurement,9 cases of 15 CEA positive patients and 3 cases of the 12 CEA negative patients had FDG metabolism,confirmed by pathology and follow-up. Conclusion:18 F-FDG dual head gamma-camera coincidence( DHC)imaging is a sensitive and effective method in the local recurrence diagnosis of postoperative rectal carcinoma,and has broad clinical application pros-pects.

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