母乳喂养与新生儿免疫

摘要

新生儿的免疫系统尚不成熟.母乳中含有多种具有抗感染作用的生物活性成分,如sIgA、乳铁蛋白、溶菌酶、低聚糖、游离脂肪酸、白细胞及细胞因子等,能为新生儿提供免疫保护.母乳的部分成分还可能与促进新生儿免疫发育有关,而母乳中的抗原成分和细胞因子则具有诱导免疫耐受的作用.%With an immature immune system, infants are susceptible to infections. Human breast-milk contains a variety of immunological active components, which can protect infants from infections. These immunological active components include slgA, lactoferrin, lysozyme, oligosaccharides, free fatty acids, leucocytes and cytokines, etc. Some particular components in breast-milk can promote the development of neonatal immune system, while antigens and cytokines in human breast-milk probably can induce immune tolerance.