This review summarizes the epidemiology, etiology, clinical manifestation, treatment, follow-up of neonatal lupus erythematosus with focus on new discoveries on the etiology of the disease in recent years including anti-SSA/Ro and anti-SSB/La antibodies, serotonin (5-hydroxytryptamine 4), apoptosis of cardiac cells, calcium channels, maternal micro-chimera, genetic variants, to improve clinician awareness of the disease.%综述新生儿狼疮病的流行病学、病因、临床表现、治疗、随访等,着重于近些年来对该病病因的新发现,包括抗干燥综合征A(SSA/Ro)抗体和抗干燥综合征B(SSB/La)抗体、血清素(5-HT4)、心肌细胞凋亡、钙通道、微嵌合体、遗传突变等方面。
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