社区获得性呼吸窘迫综合征毒素的研究进展

摘要

社区获得性呼吸窘迫综合征毒素(CARDS TX)是肺炎支原体合成的重要毒素,该毒素的合成、分布、生物活性已逐渐明确.研究发现,CARDS TX对肺炎支原体感染后的炎症反应、哮喘控制不力有一定的影响.文章综述CARDS TX的发现、结构、基本生物学活性,以及在MP肺炎、哮喘发病机制的研究进展.%The Community-Acquired Respiratory Distress Syndrome toxin (CARDS TX) is one of the most important toxins produced by the Mycoplasma pneumoniae.The synthesis,distribution and bioactivity of this toxin have been gradually studied.It has been shown that CARDS TX has impact on the inflammation induced by Mycoplasma pneumoniae infection,and poorly controlled asthma. With further study on the pathomechanism of the CARDS TX, it would become a new key in arriving early or confirmed diagnosis and treatment about Mycoplasmal pneumonia.