刺参内脏蛋白酶解液抗氧化活性研究

摘要

D-galactose subacute aging model of mice was built up for further on studying the antioxidant activities of protein hydrolysates from sea cucumber viscerahydrolysates , the capacity of SOD and GSH-Px and MDA content of mice in liver and heart were detected. Results showed that: the levels of SOD and GSH-Px activity were obviously increased in liver and heart of mice after fed hydrolysates 200 mg/kg·d every day, and MDA content was obviously decreased, suggesting that there was a remarkable antioxidant effect of protein hydrolysates from sea cucumber viscera on D-galactose subacute aging model mice.%采用小鼠D-半乳糖致衰老模型，通过测定小鼠肝脏和心脏中的超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）活性和丙二醛（MDA）含量，进一步研究了刺参内脏蛋白酶解物酶解物的抗氧化活性。表明灌胃200 mg/kg·d酶解物可明显提高小鼠肝脏和心脏中SOD和GSH-Px活力，并显著降低MDA含量。说明刺参内脏蛋白酶解物在一定程度上能够提高D-半乳糖模型衰老小鼠的抗氧化能力。