抗生素相关性肠炎并肠梗阻一例诊治分析

摘要

目的 探讨抗生素相关性肠炎(antibiotic-associated coitis,AAC)临床特点,提高诊治水平.方法 回顾分析1例AAC并肠梗阻临床资料.结果 患者为老年女性,因急性肠炎使用头孢美唑钠、莫西沙星等抗感染治疗20 d后,出现腹泻、腹胀、高热及肛门停止排便排气等症状.影像学检查证实低位性肠梗阻,肠镜检查证实AAC.经胃肠减压、调节肠道菌群等综合治疗痊愈.结论 临床医师对于具有老年、禁食、病情危重、抗生素使用多且时间长等危险因素的患者应警惕AAC的发生.对于病情的确需用者,应根据药敏结果选用抗生素.%Objective To explore the clinical characteristics of antibiotic-associated colitis (AAC), and to improve the level of diagnosis and treatment. Methods The chnical data of a patient with AAC and intestinal obstruction was respectively analyzed. Results Being an old female, the patient was treated by antibiotics for acute colitis, including cefmetazole sodium and moxifloxacin, and presented diarrhea, abdominal distension, stop of defecate and exhaust 20 days after treatment.Imaging examination showed a low ileus, and colonoscopy confirmed AAC. The patient was cured after a series of therapies including gastrointestinal decompression and adjustment of enterobacteria. Conclusion Doctors should be cautioned against AAC in patients with following risk factors, such as old age, abrosia, severe sickness, multiple and long time use of antibiotics. Patients should be treated by antibiotics narrow or spectrum antibiotic according to drug sensitive test.