Probing the fate of transplanted hematopoietic stem cells: is the combinational approach “FIT” for purpose?

摘要

Hematopoietic stem cells (HSCs)—with their self-renewal and multi-lineage differentiation potential—are top of the hematopoietic cell hierarchy. Stress conditions activate the quiescent HSCs, which in turn enter cell cycle to produce their progenies (Sawai et al., 2016).