A tRF oligomerizes Nucleolin to stabilize metastasis-favoring transcripts

摘要

Apart from bringing amino acids to ribosomes for protein biogenesis,transfer RNA(t RNA)can be cleaved into small non-coding RNAs,named as t RFs or ts RNAs.These small RNA fragments were firstly thought as random degradation products of t RNAs until the induction of certain t RFs were observed in specific stress conditions(Li et al.,2008).