Decreased peripheral mtDNA in methamphetamine use disorder

摘要

Dear Editor,Methamphetamine(METH)is the most prevalent addictive psychostimulant in China.METH use disorder(MUD)and its associated disorders constitute a significant burden to the affected individuals and their families(Paulus and Stewart,2020).Neurotransmitter system aberrations,mitochondrial dysfunction,oxidative stress,and inflammasome activation have been involved in METH-induced neurotoxicity(Shin et al.,2018;Wang et al.,2015;Wei et al.,2020).