Is glial heme oxygenase-1 suppression in neurodegenerative disorders permissive for neural repair?

摘要

‘Core’neuropathology of degenerative central nervous system(CNS)disorders The common human neurodegenerative disorders(Alzheimer’s disease(AD),Parkinson’s disease(PD),amyotrophic lateral sclerosis,etc.)vary with respect to risk factors,ages of onset,sex predilections,neuraxial regions affected,hallmark cellular inclusions,behavioral and neurological symptoms,and