新辅助化疗联合心理伦理干预对局部晚期乳腺癌患者情绪及生活质量的影响

摘要

Objective:To understand the influence of neoadjuvant chemotherapy combined with psychological and ethical intervention on mood and life quality of patients with cancer. Methods: The 120 patients with locally advanced breast cancer were randomly divided into control group ( neoadjuvant chemotherapy group) and interven-tion group ( neoadjuvant chemotherapy combined with psychological ethics intervention group) , Chemotherapy and after chemotherapy respectively adopt Zung Self -Rating Depression Scale ( SDS ) , Zung Self -Rating Anxiety Scale (SAS) and Quality of Life Core Scale (QLQ-C30) as an investigative tool, mood and quality of life of the patients were assessed. The patients' mood and life quality were investigated. Results: Emotional state intervention group patients more significantly than control group patients improved (P<0. 01) and improve life quality. Con-clusions:Neoadjuvant chemotherapy for localized breast cancer patients with psychological ethics intervention can effectively reduce the patient's anxiety and depression, and improve the life quality of patients.%目的：了解新辅助化疗联合心理伦理干预对局部晚期乳腺癌患者情绪及生活质量的影响。方法将120例局部乳腺癌晚期患者随机分为对照组(新辅助化疗组)和干预组(新辅助化疗联合心理伦理干预组)，每组各60例。化疗前和化疗后分别采用Zung抑郁自评量表( SDS)、Zung焦虑自评量表( SAS)及生活质量核心量表( QLQ-C30)作为调查工具，对两组患者情绪及生活质量进行评估。结果干预组患者情绪状况较对照组患者改善更明显( P<0.01)，且生活质量有显著提高。结论对局部乳腺癌新辅助化疗患者进行心理伦理干预，能有效减轻患者的焦虑及抑郁情绪，并可提高患者的生活质量。