保元汤加减对卡氏肺孢子虫消长的实验研究

摘要

目的 寻找调节机体免疫状态、抑制卡氏肺孢子虫（Pc）繁殖的中药，用以防止卡氏肺孢子虫肺炎（PcP）的发生，提高包括艾滋病病人在内的免疫功能低下病人的生存质量。方法 分别给PcP模型建立前后的两组大鼠保元汤加减煎剂灌胃，8周后观察两组大鼠的死亡率及肺涂片中Pc的数量。结果 保元汤加减煎剂可使大鼠的死亡率降为零，肺涂片中Pc数明显少于对照组。结论 该中药对抑制Pc的生长、繁殖具有一定的作用。%Aim In order to find traditional Chinese medicine to regulate theimmunity condition in body and prevent the happen of PcP,the experiment was developed.Methods Add-subtract Baoyuantang was gived before and after the PcP model established to two growps .8 weeks later,the death rate of mice and the number of Pc was observed. Results Traditional Chinese medicine used in this experiment could make the death rate of mice reduced to zero. The number of Pc on lungs smear was less obviously than that of control (PcP model group).Conclusion Add-subtract Baoyuantang had the effect of preventing the multiplying of Pc.