To clarify the infection source and risk factors of transmission in a brucellosis outbreak in Dawn County , Xiaogan City during the periods from October 2010 to August 2011 which was the first outbreak in Hubei Province since 1950s , we conducted case searching , epidemiologic investigation and retrospective case-control study . There were 9 brucellosis patients in the same village in this outbreak , including 1 suspected case and 8 laboratory-confirmed cases . Two strains of B .melitensis biovar 3 were cultured in the blood of 2 confirmed cases . The case-control study showed that OR value of contacting sheep was 7(1.02-52 .59)and the ways of contacting were feeding the introduced sheep and cleaning the sheepfold . The current goats in the same village were detected positive for Brucella antibody . Because the feeding of introduced goats flock was the source of this brucellosis outbreak , we should strengthen the surveillance of the population at high risk and quarantine of the sheep or goats flock .%目的 调查湖北省自1950年后的首起布鲁菌病暴发疫情的感染来源和传播的危险因素,2011年暴发发生在湖北省孝感市大悟县.方法 采用病例搜索、流行病学调查和回顾性病例对照研究.结果 本起人间布病暴发有同村9名病例,其中疑似病例1例和实验室确诊病例8例,其中2例血培养出布鲁氏菌羊种3型.病例对照研究显示接触羊的OR=7(1.02~52.59),主要接触方式为对引入羊群进行饲养和清扫羊圈.同村现存羊检测布鲁菌血清抗体阳性.结论 引入羊群的饲养是发生布鲁氏菌病疫情的主要因素,应加强对高危人群的监测和对羊群的检疫.
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