Synthesis and Crystal Structure of N-2-（4-Chlorophenyl）-1-（1-methylcarbamoyl-2-phenyl-ethylcarbamoyl）-3-phenyl-cyclopropyl-benzamide

摘要

N-[2-（4-chlorophenyl）-1-（1-methylcarbamoyl-2-phenyl-ethylcarbamoyl）-3-phenyl-cyclopropyl]benzamide,C33H30ClN3O3,has been synthesized and characterized by IR,1H NMR,13C NMR and single-crystal X-ray diffraction.The crystal is of triclinic,space group P1 with a = 11.646（2）,b = 13.795（3）,c = 14.559（3）,α = 76.422（4）,β = 78.028（4）,γ = 74.500（4）°,V = 2164.6（7）3,Z = 3,Mr = 552.05,Dc = 1.270 g/cm3,λ = 0.71073 ,μ（MoKα）= 0.171 mm–1,F（000）= 870,the final R = 0.0469 and wR = 0.0805 for 5554 observed reflections with I 2σ（I）.The N–H and oxygen atoms are involved in one-dimensional intermolecular hydrogen bonds,which further stabilize the structure.