利拉鲁肽联合二甲双胍治疗肥胖2型糖尿病伴阻塞性睡眠呼吸暂停综合征1例报告

摘要

T2DM和阻塞性睡眠呼吸暂停综合征(OSAS)均是具有潜在危险的现代常见病,并常常在肥胖病人中同时存在.本文报告1例肥胖T2DM伴OSAS的患者,经人胰高糖素样肽-1类似物(利拉鲁肽)联合二甲双胍治疗3个月,血糖控制平稳、体重下降.该治疗方案为解决此类患者的问题提供了新的选择.%Both type 2 diabetes mellitus (T2DM) and obstructive sleep apnea syndrome (OSAS) are common diseases having high potential hazards and clinically they are always co-existing, especially in obese patients. In this report, an obese patient with T2DM and OSAS was treated with human glucagon-like peptide-1 analogue liraglutide plus metformin for 3 months, and the effect was good in glycemic control and weight loss. Such a successful treatment may provide a new option for treating the similar patients.