糖尿病前期与糖尿病相关因素的研究

摘要

目的 探讨糖尿病前期和糖尿病的相关因素. 方法 根据ADA 2003年分类标准,对糖尿病前期和糖尿病相关因素进行Logistic回归分析.总共纳入204名对象,正常血糖66名,糖尿病前期100例,糖尿病患者38例. 结果 3种不同的血糖状态在TG、胰岛素抵抗指数(HOMA-IR)、胰岛素分泌指数(HOMA-β)、血清总免疫球蛋白E(IgE)和C-RP的分布差异均具有统计学意义(P＜0.05或P＜0.01)；多变量Logistic回归分析结果表明,IR与IS是糖尿病前期及糖尿病的危险因子(P＜0.05).结论 HOMA-IR与HOMA-β是公认的糖尿病的危险因子.%Objective To explore the risk factors related to prediabetes and diabetes under ADA 2003 classification criteria. Methods A total of 204 subjects aged 55 to 75 years were analyzed in the current study. One-way ANOVA, chi-square test and non-parametric test and logistic regression analysis were used for data analysis. Normal blood glucose was defined as FPG<5. 6 mmol/L and 2 hPG<7. 8 mmol/L, prediabetes was defined as 5. 6 mmol/L≤FPG<7. 0 mmol/L or 7. 8 mmol/L≤2 hPG