牙本质液及其生理病理学意义的研究进展

摘要

牙本质液是存在于牙本质小管内的微量流体，其确切成分尚不明确。牙本质液在牙本质小管内自牙髓向浅层牙本质流动形成的牙髓正压力是保证牙髓-牙本质微环境内稳态的生理学基础。目前普遍认为，牙本质液发生异常流动是牙本质感觉过敏症产生的病理学基础；此外，牙本质液自内而外流动产生的正向组织压还可影响牙体组织修复粘结的效率。本文以牙本质液的生理、病理学性质为基础，就牙本质感觉过敏症的发生机制以及牙本质液影响修复粘结效率的研究进展作一综述。%Dentinalfluidisthefluidexistingindentinaltubules.Itisregardedasanimportantsubstance in sustaining the homeostasis of dental pulp.Abnormal dentinal fluid movement is the pathological basis of dentin hy-persensitivity.Furthermore,dentinal fluid plays an important role in adhesion efficiency of dentin with dental restora-tive materials.This review summarizes its roles and underlining mechanisms on dentinal hypersensitivity and dentin ad-hesion based on recent research progress.