激光酸蚀联合纳米管处理的钛种植体骨结合能力的研究

摘要

AIM:To compare the osseointegration effects of laser/acidanotubes-treated ( LAN) and sand-blasted/acid-treated ( SLA) titanium implant surfaces. METHODS:4 LAN implants were embedded in the left tibial bone of 4 Beagle dogs, while 4 SLA implants were embedded in the right tibial bone of the dogs. At 2 and 4 w after op-eration, 2 animals were sacrificed respectively and the tibial bones were taken. Bone ossointegration was observed by histological method. RESULTS:The percentage of bone area ( BA) and bone-implant contact ( BIC) in LAN group were significantly higher than those in SLA group at both 2 and 4 w (P<0. 05) after implantation. CONCLUSION:Laser/acidanotube-treated implants are more effective for ossoingrationthan than sandblasted/acid-treated implants.%目的：：研究激光酸蚀联合纳米管种植体( LAN)与喷砂酸蚀种植体( SLA)在不同时期骨结合的差异。方法：取Beagle犬4只，分别在每只犬后腿的左侧胫骨植入4枚LAN处理的钛种植体( LAN组)，右侧胫骨植入4枚SAL处理的钛种植体作为对照( SLA组)；分别于术后2、4周各随机处死2只动物，取出胫骨后，采用EXAKT切磨系统制作含种植体的骨组织切片；通过甲苯胺蓝染色法观察各种植体的骨结合情况，并比较两种不同处理方法的种植体在不同时期骨结合的差异。结果：术后2、4周， LAN组的种植体-骨结合率(BIC%)、骨面积百分数(BA%)均高于SLA组(P<0.05)。结论：激光酸蚀联合纳米管处理的种植体(LAN)相比喷砂酸蚀处理的种植体( SLA)具有更好的骨结合效果。