不同程度高三酰甘油血症患者的生化指标比较

摘要

Objective To compare the anthropometric indexces and lipid metabolism among hypertriglyceri-demia subjects with different blood triglyceride ( TG) levels. Methods 101 subjects with hypertriglyceridemia were chosen to this study. The anthropometric measurements of body height, weight, body mass index ( BMI), waist circumference (WC) ,blood TG, total cholesterol( TC) , high-density and low-density lipoprotein cholesterol ( HDL-C, LDL-C) ,apolipoprotein A1 ,B>A2 ,C2 ,C3 ,E( ApoA1 ,B,A2 ,C2 ,C3 ,E) were measured. Then all subjects were divided into two groups according to 1.70 mmol/L≤TG≤2.25 nunol/L and TG≥2. 26 mmol/L,compare the indices mentioned above between the two groups. Results The enrolled subjects of the two groups were overweight according to BMI, and abdominal obesity according to WC. In the group with TG≥2.26mmol/L,the contents of blood TG,Apo E,C2, C3 ,A II were significantly higher than those in the group with 1. 70mmol/L≤TG≤2. 25mmol/L(P <0. 01 or P < 0.05), while no other significant difference were observed between the two groups. Conclusion The blood ApoE, C2, C3, A2 among hypertriglyceridemia subjects were concomitant with levels of TG and thus provide some helpful parameters to evaluate the severity of hypertriglyceridemia.%目的 对不同程度的高三酰甘油血症患者的人体测量及血脂生化指标进行比较分析.方法 选择高三酰甘油血症患者101例,取空腹血测定血三酰甘油(trG)、总胆固醇(TC)、高密度及低密度脂蛋白胆固醇( HDL-C、LDL-C)、载脂蛋白A1、B、A2、C2、C3、E( ApoA1、B、A2、C2、C3、E)等指标,并进行身高、体质量、腰围等人体测量,计算体质量指数( BMI),按1.70 mmol/L≤TG≤2.25 mmol/L和TG≥2.26 mmoL/L将研究对象分为临界高脂组和高脂血症组,比较两组人群上述人体测量及血脂生化指标的差异.结果 两组人群的BMI处于超重水平,从腰围判断属于腹型肥胖；高脂血症组人群的血TG、ApoE、C2、C3、A2均显著高于临界高脂组(P＜0.01或P＜0.05),其余指标两组间差异无统计学意义(P＞0.05).结论 高三酰甘油血症患者的血ApoE、C2、C3、A2与三酰甘油水平密切相关,在反映高三酰甘油血症患者病情方面具有一定的参考价值.