维吾尔族、汉族老年人群亚临床甲状腺功能减退症与骨质疏松的相关性研究

摘要

目的：探讨新疆乌鲁木齐地区汉族、维吾尔族老年亚临床甲状腺功能减退症（老年亚临床甲减）患者促甲状腺激素水平（TSH）与骨密度（BMD）的相关性。方法选择住院的60岁以上老年人207例。根据甲状腺功能测定结果将其分为病例组即亚临床甲状腺功能减退症患者101例，对照组为甲状腺功能正常（甲功正常）患者106例，分析两组年龄、性别、民族、体质量指数（ BMI）、血压、血糖、血钙、血磷及骨质疏松发生情况。结果两组年龄、性别、民族、BMI、血压、血糖、血钙、血磷比较差异无统计学意义（P＞0．05），两组间具有可比性。亚临床甲减组患者与甲功正常患者组骨密度比较，差异有统计学意义（P＜0．05）。汉族亚临床甲减组与甲功正常患者组骨密度比较，差异有统计学意义（P＜0．05），而维吾尔族组骨密度比较差异无统计学意义（ P＞0．05）。结论亚临床甲减可能是汉族老年人群骨质疏松的危险因素。%Objective To discuss the correlation between subclinical hypothyroidism (SCH) and osteoporo-sis in the elderly of Han and Uygur in Xinjiang Urumqi .Methods A total of 207 patients aged 60 years or older were selected from our hospital and divided into two groups according to the result of Thyroid function test .One hundred and one cases with subclinical hypothyroidism were chosen as case group and 106 cases of normal thyroid function were chosen as control group.The age,gender,nationality,BMI,blood pressure,blood glucose,blood calcium and blood phosphorus between the two groups were analysed .Results There was no significant difference with regard to the age,gender,nationality,BMI,blood pressure,blood glucose,blood calcium and blood phosphorus between the two groups (P>0.05).The difference of bonemineral density between the two groups was statistically significant (P<0.05).The bone mineral density was statistically different (P<0.05) in Han between the two groups,but the differ-ence was not statistically significant (P>0.05) in Uygur.Conclusion The subclinical hypothyroidism may be a risk factor of osteoporosis in Han elderly .