新疆地区心房颤动与血清胱抑素C的相关性研究

摘要

目的 探讨新疆地区心房颤动患者心房颤动的发生与血清胱抑素C的相关性.方法 选择维吾尔族、汉族心房颤动患者各100例作为心房颤动组,维吾尔族、汉族非心房颤动患者各100例作为对照组,收集各组患者的一般临床资料包括年龄、性别、低密度脂蛋白、血清胱抑素C、D-二聚体等.采用Logistic回归分析心房颤动与血清胱抑素C的相关性.结果 维吾尔族、汉族心房颤动组与对照组比较,血清胱抑素C水平差异有统计学意义(P<0.05),心房颤动组血清胱抑素C显著高于非心房颤动组.多因素Logistic回归分析结果发现,血清胱抑素C(OR=9.964,95%CI=1.749~56.756,P<0.05)是心房颤动的独立危险因素.结论 在新疆地区维吾尔族和汉族人群中,血清胱抑素C的升高可能是心房颤动的危险因素.%Objective To investigate the correlation between atrial fibrillation and serum cystatin C in Uygur and Han patients with atrial fibrillation in Xinjiang.Methods 100 cases of Uygur and Han patients with atrial fibrilla-tion were enrolled in this study.100 cases of Uygur and Han non-atrial fibrillation were used as control.The age,sex,low density lipoprotein,serum cystatin C,D-dimer and other data were recorded.Logistic regression analysis was used to ana-lyze the correlation of atrial fibrillation and serum cystatin C.Results There was a significant difference in serum Cys-tatin C between Uygur and Han group with atrial fibrillation and non-atrial fibrillation group(P<0.05).The serum cys-tatin C level was significantly higher in atrial fibrillation group than that in non-atrial fibrillation group.Multivariate lo-gistic regression analysis showed that serum cystatin C was an independent risk factor for atrial fibrillation(OR=9.964, 95%CI=1.749-56.756,P<0.05).Conclusion Serum cystatin C may be a risk factor for atrial fibrillation in the Xinjiang Uygur and Han populations.