寡霉素的研究进展

摘要

寡霉素抗生素组合物是一类二十六元环大环内酯类抗生素,具有强烈的抗肿瘤、抗真菌、呼吸抑制作用及杀虫等生物学活性,被广泛应用于科学研究当中.本文对寡霉素的生物学活性、产生菌及生物合成的研究进展进行了综述.%Oligomycins are a series of 26-membered macrocyclic lactones. They display strong antifungal, anti-tumor, respiratory inhibitory and insecticidal activities, and are widely used in scientific research. In this paper, we review the research advances in the biological activities, producing strains and biosynthesis of oligomyicns.