Polyhydroxyalkanoate(PHA)is a type of polymer which can be synthesized by a variety of microbes.This new kind of material can be used as a substitute for the traditional petrochemical plastics because of its complete bio-degradability.PHA biosynthesis paths in different microbes have been studied widely and extensively to these days.In order to reduce PHA price and realize industrialisation,many researches have been focused on screening high-productivity strain and using cheap carbon source to synthesis PHA.This review introduces the PHA biosynthesis pathways and advance in biosynthesis of PHA.%聚羟基烷酸酯(PHA)是一类在众多微生物细胞内可合成的聚酯,由于其可完全生物降解,是一类可替代传统塑料的新型生物材料。该类聚酯在不同的微生物细胞内的生物合成途径已经被广泛和深入地研究。为降低其生产成本,实现工业化生产,筛选更高产的菌株和利用廉价碳源来合成PHA成为近年来的研究重点。本文介绍了PHA的在微生物细胞内的合成途径以及最近几年来生物合成PHA的研究进展。
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