羟肟酸类化合物的合成与应用研究进展

摘要

Hydroxamic acid compounds,which contain the functional groups of hydroxyl oximido with high coordination activity,can chelate with metal ions to form a stable ring and have extensive applied values. It is a very reactive chelating agent. The structure characteristics and chemical properties of hydroxamic acid compounds were introduced. The synthesis methods of hydroxamic acid and hydroxamic acid polymer were reviewed,with emphasis on hydroxylamine method. The updated progresses of their application were also reviewed in the fields of medicine,flotation and metallurgy and the function mechanism of hydroxamic acid on mineral surface to flotation is recommended In order to broaden the scope of its application in less new product,high production costs and low toxicity in the process of preparation should be paid more attention. New product,high efficiency,green industry should be the direction of preparation of hydroxamic acid.%羟肟酸类化合物具有配位活性良好的羟肟基，可以与多种金属离子形成稳定的螯合环，是一类高活性螯合剂，具有广泛的应用价值。本文介绍了羟肟酸类化合物的结构特征与化学性质；综述了羟肟酸及羟肟酸高分子的合成方法，介绍了羟胺法合成技术的国内外研究进展；同时详述了羟肟酸类化合物在医药、金属矿物浮选、冶金领域中的应用新进展，认为应深入研究羟肟酸类化合物与矿物的作用机理，以拓宽其在矿物浮选中的应用范围。最后指出羟肟酸类化合物存在新型产品少、生产成本高和具有低毒性等问题，在未来的研究中应向设计合成新型、高效、绿色的羟肟酸类化合物方向发展。