Interleukin-22 from bench to bedside:a promising drug for epithelial repair

摘要

Cellular and Molecular Immunology(CMI),the official journal of theChinese Society of Immunology,was established in 2004.CMI hasnow become one of the leading international journals in the fieldand publishes high-quality original articles and reviews.The veryfirst research article published in the inaugural issue of CMI wasfrom our group and described,for the first time,the protectiveeffect of interleukin-22(IL-22)on the epithelium in the liver.1Fascinatingly,14 years later,the first-in-human phase I clinicalstudy of human IL-22-Fc dimer(F-652)in healthy subjects is alsopublished in CMI.2 We are very excited to see these interestingstudies of IL-22 from bench to bedside published in CMI alongsideits strong growth as a journal over the last 14 years.