Electrospun Fibrous P (LLA-CL) Tubular Scaffold

摘要

Electrospinning has been recognized as an efficient technique for fabricating polymer nanofibers. In this study, small diameter fibrous tubular scaffolds have been obtained from P (LLA-CL) nanofibers through multi-jets electrospinning. As SEM images shown, the scaffolds with excellent morphology were constructed with nanofibers absolutely. The pore size is a very important factor for nanofibers tube application in tissue engineering. Therefore, gelatin which is a biocompatible and biodegradable biomaterial was selected to adjust the pore size of the scaffold during electrospinning process. After taken off from collector, the scaffold was put into water to remove gelatin. After drying under vacuum, a tubular scaffold with better pore size property can be received. Mechanical properties of this kind of nanofibers composited films were tested. The broken stress increased with increasing content of P (LLA- CL) nanofibers, and the broken strain decreased with this changing. The films at wet condition have less broken stress and more strain than at dry condition.