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Control of COVID-19 Outbreak for Preventing Collapse of Healthcare Capacity based on Social Distancing, Confinement and Testing-Quarantining

机译:基于社会疏远,监禁和检测隔离的防止医疗保健能力崩溃的Covid-19爆发控制

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This work is a contribution to the call to The IFAC-CSS Corona Control Community Project in February 2020. Scientific evidence to the effectiveness of the three main non-pharmacological tools to mitigate a pandemic is given. A control system to control the Covid-19 outbreak caused by the Sars-CoV2 virus, called Coronavirus, is proposed, for preventing collapse of the health systems and saturation of Intensive Therapy Units (ITUs) capacity. The proposed system is based on the three existing non-pharmacological tools for the mitigation of epidemics and pandemics: social distancing, confinement and testing with isolation of a population in which there is community circulation of the virus. Both in the analysis and in the design of the control system, the mathematical model SEIRD (Susceptible - Exposed - Infected - Recovered - Deceased) is used, which describes the dynamics of a pandemic, adjusted in this work to the behavior in space and time of the Sars-CoV2. In this work the incidence and impact of testing with isolation (or testing-quarantining) is incorporated in the model. The proposed control system uses, as a feedback signal, the demanded quantity of critical beds and ITUs, which is compared with the available beds capacity to generate the error signal as input to a PID controller. As control actions, five Phases of Social Distancing and Confinement (SD&C) are proposed, which must be applied by the public authority. The control system thus generates a SD&C decision sequence or policy, which can be applied once a week or every fortnight. Simulation results showing the practical feasibility and good performance of the proposed control system are given, preventing collapse of Healthcare Capacity based on Social Distancing, Confinement and Testing-quarantining as control actions.
机译:这项工作是对2月2020年2月对IFAC-CSS电晕控制社区项目的贡献。给出了三个主要的非药理学工具的有效性,以减轻大流行的科学证据。提出了一种控制由SARS-COV2病毒引起的Covid-19爆发的控制系统,称为冠状病毒,用于防止健康系统崩溃和强化治疗单元(ITU)的饱和度。该拟议的系统基于三个现有的非药理学工具,用于减轻流行病和流行病:社会疏散,监禁和测试,孤立于群体循环病毒的群体。在分析和控制系统的设计中,使用数学模型SEIRD(易感 - 暴露感染 - 已恢复死亡),其描述了大流行的动态,在这项工作中调整到空间和时间的行为SARS-COV2。在这项工作中,使用隔离(或测试隔离)测试的发病率和影响在模型中。所提出的控制系统用作反馈信号,所需数量的关键床和ITU,其与可用床的能力进行比较,以产生误差信号作为输入到PID控制器。作为控制行动,提出了五个社会疏散和监禁(SD&C),必须由公共机构申请。因此,控制系统产生SD&C决策序列或策略,可以每周或每两周应用一次。仿真结果表明了所提出的控制系统的实用可行性和良好性能,防止基于社会疏散,监禁和检测作为控制行动的医疗保健能力崩溃。

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