Advances in Modeling Dielectric Response of Biological Structures at Microscopic Level

摘要

The use of dielectric response as a tool for studying molecular and cellular parameters is a well-established approach on continuing attention. A valuable approach, which is used to gather inside mechanisms of dielectric response and to provide the average electrical parameters of both the cell membrane and the intra-cellular and extracellular medium, is represented by the modeling one. In this paper we will describe some advances in models able to describe the dielectric behavior of different bio-systems, in particular: molecular models for Na+ and Cl- ion in water and water in proximity of charged surfaces and cell continuum microdosimetric models.