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ANALYSIS OF ELECTROKINETIC FLUID FLOW IN T-SHAPED DNA CHIPS

机译:T形DNA芯片中的电动流体流动分析

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Lab-on-chip devices promise for many novel applications concerning the transport of the liquid samples and other solutions in the order of micro-scale dimensions. One of the efficient methods for transporting fluid in the samples is through electrokinetic effects, where an electric field will be applied to charged ions such as DNA, a negatively charged ion or proteins. These ions are carried over in the microchannel by the application of electric fields through the entire solution from inlet via probe region for its detection to outlet and the determination of concentration distribution. COMSOL, commercially available multiphysics software, with its specific MEMS and Chemical Engineering modules were employed and simulated for the analysis of fluid velocity and ionic concentration throughout the channel of various shapes. The ionic fluid concentrations and velocities in the channel and at the outlet are plotted against the potential differences across the two inlets in which DNA sample was introduced from one inlet and a buffer solution was supplied from another inlet..
机译:实验室内容有助于按照微尺度尺寸的顺序传输液体样品和其他解决方案的许多新应用。用于在样品中运输流体的有效方法之一是通过电动效应,其中电场将施加到带上的离子,例如DNA,带负电荷的离子或蛋白质。这些离子在微通道中通过从入口通过探针区域施加通过探针区域来施加电场,以检测出口和浓度分布的测定。使用具有其特定MEMS和化学工程模块的COMSOL,市售的多体软件,并模拟在各种形状的通道中分析流体速度和离子浓度。在通道和出口处的离子流体浓度和速度彼此绘制在两个入口上的两个入口上的电位差异,其中从一个入口中引入DNA样品和缓冲溶液。

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