首页> 外文会议>IEE Colloquium on Qualitative and Quantitative Modelling Methods for Fault Diagnosis, 1995 >The Usefulness of the Auditory N100 and P200 Component as Measures of Sensory Gating
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The Usefulness of the Auditory N100 and P200 Component as Measures of Sensory Gating

机译:听觉N100和P200组件作为感觉门控措施的有用性

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A sensory gating deficit has been repeatedly demonstrated in schizophrenia patients, especially for the P50 component of the auditory evoked response. In the present study, we investigate whether the N100 and P200 can be used as gating measures as well, and what kind of differences exist between normal controls and schizophrenia patients for these gating measures. We also explore whether gating is absent when sequences of non-identical stimuli are presented. It was found N100 and P200 showed significantly more gating and less day-to-day variability than P50 for normal subjects. Large day-to-day and inter-subject variability was observed in schizophrenia patients. The gating indexes for the non-identical stimuli were not significantly different from the corresponding indexes for identical stimuli
机译:在精神分裂症患者中反复证明了感觉门控缺陷,特别是对于听觉诱发反应的P50成分。在本研究中,我们调查N100和P200是否也可以用作门控措施,以及正常对照和精神分裂症患者在这些门控措施上存在哪些差异。我们还探讨了当呈现不同刺激序列时是否不存在门控问题。研究发现,与正常人相比,N100和P200的门控显着多于P50,日常变异性也较小。在精神分裂症患者中观察到较大的日常差异和受试者间差异。不同刺激的门控指标与相同刺激的对应指标没有显着差异

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