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The integration analysis of multiple species phosphorylation sites

机译:多物种磷酸化位点的整合分析

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Protein phosphorylation plays a key role in sucrose-mediated transcriptional regulation of a phloem-specific proton-sucrose symporter. We evaluate the conservation of phosphorylation sites and its surrounding amino acids stretch through statistic analysis in this paper. Ten eukaryotic model species protein sequences were downloaded and the sequences which have ortholog were reserved for the anaysis. To compare the conservation of phosphorylation sites and its flanking sequences, we create two indexes named conservation score (C-score) and conservation Z-score (CZ-score) to evaluate the conservation of phosphorylation sites and its flanking sequences. The result shows that phosphorylated sites may be much better conserved than the unphosphorylated sites. The flanking sequences of phosphorylation site don't reflect the same trend.
机译:蛋白质磷酸化在韧皮部特异性质子-蔗糖同向转运体的蔗糖介导的转录调控中起关键作用。通过统计分析,我们评估了磷酸化位点及其周围氨基酸的保守性。下载了十个真核模型物种的蛋白质序列,并保留了具有直向同源物的序列用于分析。为了比较磷酸化位点及其侧翼序列的保守性,我们创建了两个指标,称为保守性得分(C分数)和保守性Z分数(CZ分数),以评估磷酸化位点及其侧翼序列的保守性。结果表明,磷酸化位点的保守性可能比未磷酸化位点更好。磷酸化位点的侧翼序列没有反映出相同的趋势。

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